This medication is used to prevent kidney stones in people with a certain inherited disorder (cystinuria). Cystinuria occurs when there is too much of a certain natural substance (the amino acid cystine) in the urine, leading to formation of kidney stones.
Are side effects harmful?
Common side effects include upset stomach, dry mouth, and drowsiness. A side effect is considered serious if the result is: death; life-threatening; hospitalization; disability or permanent damage; or exposure prior to conception or during pregnancy caused birth defect.
What is Tiopronin for?
What does potassium citrate treat?
Potassium citrate is used to treat a kidney stone condition called renal tubular acidosis. It is also used to prevent kidney stones that may occur with gout. Potassium citrate is a urinary alkalinizer. It works by making the urine more alkaline (less acid).
What is thiola EC?
THIOLA EC is a reducing and complexing thiol indicated, in combination with high fluid intake, alkali, and diet modification, for the prevention of cystine stone formation in adults and pediatric patients 20 kg and greater with severe homozygous cystinuria, who are not responsive to these measures alone. (
Is cystinuria a chronic disease?
Cystinuria is a chronic condition and many affected people experience recurrent cystine stones in the urinary tract (kidneys, bladder and ureters). In rare cases, frequent kidney stones can lead to tissue damage or even kidney failure.
When do drug side effects start?
Side effects can happen at any time. They can occur when you first take a medicine, with changes in dosage, or if you stop taking the medicine suddenly or too soon. If you begin to take other prescriptions or non-prescription products, interactions among the medicines may cause side effects as well.
What drugs side effects?
A side effect is usually regarded as an undesirable secondary effect which occurs in addition to the desired therapeutic effect of a drug or medication. Side effects may vary for each individual depending on the person’s disease state, age, weight, gender, ethnicity and general health.
How does penicillamine chelate copper?
3.5. Penicillamine or β,β-dimethylcysteine (Cuprimine) is derived from the hydrolytic degradation of penicillin. The d-isomer is an effective chelating agent for copper, iron, lead, mercury, and zinc, and will increase the excretion of these metals in the urine.
What are the side effects of taking potassium citrate?
What are the possible side effects of potassium citrate?
- confusion, anxiety, feeling like you might pass out;
- uneven heartbeat;
- extreme thirst, increased urination;
- leg discomfort;
- muscle weakness or limp feeling;
- numbness or tingly feeling in your hands or feet, or around your mouth;
Is potassium citrate safe to take?
This medication may cause high potassium levels in the blood (hyperkalemia). Tell your doctor right away if any of these serious side effects occur: muscle cramps/weakness, severe dizziness, slow/irregular heartbeat, mental/mood changes (e.g., confusion, restlessness), tingling of the hands/feet, unusually cold skin.
Is cystinuria a kidney disease?
What happens if you drink alcohol while taking Thiola?
Avoid drinking alcohol 2 hours before and 3 hours after taking Thiola. Get emergency medical help if you have signs of an allergic reaction: hives, rash; fever, swollen glands, joint pain; difficult breathing; swelling of your face, lips, tongue, or throat.
What is the indication of thithiola EC?
THIOLA EC is indicated in pediatric patients weighing 20 kg or more with severe homozygous cystinuria, in combination with high fluid intake, alkali, and diet modification, for the prevention of cystine stone formation who are not responsive to these measures alone.
What should I do if I take Thiola?
Swallow the tablet whole and do not crush, chew, or break it. Drink plenty of liquids while you are taking Thiola. You will need frequent urine tests. Store at room temperature away from moisture and heat. What happens if I miss a dose?
What are the ingredients in Thiola EC?
Each THIOLA EC tablet contains 100 or 300 mg of tiopronin. The inactive ingredients in THIOLA EC tablets include lactose monohydrate, hydroxypropyl cellulose, hydroxypropyl cellulose (low substitute), magnesium stearate, hydroxypropyl methylcellulose E5, methacrylic acid: ethyl acrylate copolymer (Eudragit L 100-55), talc, triethyl citrate.
